Germ cell tumours

Introduction to germ cell tumours

This tutorial costs £10.00


Meiosis in an oocyte (Wellcome Image Library).

Germ cell tumours are rare and account for 2–5% of all ovarian malignancies. They all originate from the oocyte (the 'germ[inating] cell') within the ovary, and are classified according to the type of cell produced.

The tumour develops following a parthenogenetic pregnancy and partial embryogenesis, which then develops abnormally into a neoplasm.

Learning objectives

When you have completed this tutorial you will be able to:

  • explain the different types of germ cell tumours and their origin
  • discuss the incidence of these tumours and investigations required for this particular type of ovarian tumour
  • explain the appropriate treatment
  • counsel a woman and her family regarding the long-term effects of treatment on future fertility and the potential risks of the treatment itself
  • know the long-term prognosis of treatment for a germ cell tumour.

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